BDBM724206 2-(((1R,5S,6S)-6-(6-((4-Chloro-2-fluorobenzyl)oxy)-3-methylpyridin-2-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methyl)-4-methoxy-1-(((S)-oxetan-2-yl)methyl)-1H-benzo[d]imidazole-6-carboxylic acid::US20250066338, Example 19

SMILES COc1cc(C(=O)O)cc2c1nc(CN1C[C@@H]3[C@H](C1)[C@H]3c1nc(OCc3ccc(Cl)cc3F)ccc1C)n2C[C@@H]1CCO1

InChI Key InChIKey=IAMQLJPJFOJTBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724206   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Astrazeneca

US Patent
LigandPNGBDBM724206(2-(((1R,5S,6S)-6-(6-((4-Chloro-2-fluorobenzyl)oxy)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the effects of compounds on the activity of the human phosphodiesterase-3A is quantified by measuring the formation of 5′AMP from cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
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