BDBM724205 2-(((1R,5S,6r)-6-(6-((4-Chloro-2-fluorobenzyl)oxy)-3-fluoropyridin-2-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methyl)-1-((1-ethyl-1H-imidazol-5-yl)methyl)-4-methoxy-1H-benzo[d]imidazole-6-carboxylic acid::US20250066338, Example 17

SMILES CCn1cncc1Cn1c(CN2C[C@@H]3[C@H](C2)[C@H]3c2nc(OCc3ccc(Cl)cc3F)ccc2F)nc2c(OC)cc(C(=O)O)cc21

InChI Key InChIKey=VHDCPEUUYOEQQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724205   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Astrazeneca

US Patent
LigandPNGBDBM724205(2-(((1R,5S,6r)-6-(6-((4-Chloro-2-fluorobenzyl)oxy)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the effects of compounds on the activity of the human phosphodiesterase-3A is quantified by measuring the formation of 5′AMP from cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
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