BDBM723595 US20250064789, Compound 169

SMILES O=C(NCc1ccccn1)C(=O)[C@@H](Cc1ccccc1)NC(=O)C1(NC(=O)C2CCC(F)(F)CC2)CC1

InChI Key InChIKey=IYFNRUHNMPLXTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723595   

TargetReplicase polyprotein 1a(2019-nCoV)
Westvac Biopharma Co.

US Patent
LigandPNGBDBM723595(US20250064789, Compound 169)
Affinity DataIC50: 2.26E+4nMAssay Description:The recombinant SARS-CoV-2 Mpro (with a final concentration of 750 nM) was mixed with a series of dilutions for each compound in 25 μL assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM723595(US20250064789, Compound 169)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed