BDBM723537 US20250064789, Compound 111

SMILES C[C@@H](NC(=O)CC1CCC(F)(F)CC1)C(=O)N[C@H](Cc2ccccc2)C(=O)C(=O)NCc3ccccn3

InChI Key InChIKey=IQVDFTGKCOAFQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723537   

TargetReplicase polyprotein 1a(2019-nCoV)
Westvac Biopharma Co.

US Patent
LigandPNGBDBM723537(US20250064789, Compound 111)
Affinity DataIC50: 2.53E+4nMAssay Description:The recombinant SARS-CoV-2 Mpro (with a final concentration of 750 nM) was mixed with a series of dilutions for each compound in 25 μL assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM723537(US20250064789, Compound 111)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed