BDBM723401 US12234230, Compound 14

SMILES CC(c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3CCC3)c1)C2=O)N1CCC(F)(F)[C@H](C)C1

InChI Key InChIKey=MUSGDLKMVJJJAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 723401   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 723401BDBM723401(US12234230, Compound 14)
Affinity DataIC50: 60nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent