BDBM723395 US12234230, Compound 8

SMILES Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cccc3C(F)(F)F)C2=O)c1)C1CCC1

InChI Key InChIKey=WGWGRKSPJWZPCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 723395   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandPNGBDBM723395(US12234230, Compound 8)
Affinity DataIC50: 27.5nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
Go to US Patent