BDBM723257 US20250059220, Compound 369

SMILES CS(=O)(=O)c1ccc(COc2cc(-c3cnn[nH]3)cc3c(Br)c(C(F)(F)P(=O)(O)O)sc23)cc1

InChI Key InChIKey=ZIPCRVPKLAFEMK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723257   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723257(US20250059220, Compound 369)
Affinity DataIC50: 2.5nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723257(US20250059220, Compound 369)
Affinity DataIC50: 2.5nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent