BDBM722824 US20250059213, Compound 47

SMILES O=C(N[C@H](CC(=O)N1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)B(O)O)c1cnccn1

InChI Key InChIKey=UIVPTILEHQDKJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 722824   

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722824(US20250059213, Compound 47)
Affinity DataIC50: 5.00E+4nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722824(US20250059213, Compound 47)
Affinity DataIC50: 2.75E+3nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent