BDBM722805 US20250059213, Compound 21

SMILES O=C(N[C@@H](CCCc1ccccc1)B(O)O)[C@@H](CC(=O)N1CCOCC1)NC(=O)N1CCOCC1

InChI Key InChIKey=XYRSHTDDNWAVRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 722805   

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722805(US20250059213, Compound 21)
Affinity DataIC50: 50nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722805(US20250059213, Compound 21)
Affinity DataIC50: 50nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent