BDBM722767 US20250059204, Compound 44::US20250145637, Example 15

SMILES COc1cc2c(cc1S(=O)(=O)Nc1noc3cc(Cn4cccn4)c4c(c13)OCC4)CCC2

InChI Key InChIKey=SDLXKGFWMMMSSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 722767   

TargetHistone acetyltransferase KAT6A(Human)
Aurigene Oncology

US Patent
LigandPNGBDBM722767(US20250059204, Compound 44 | US20250145637, Exampl...)
Affinity DataIC50: 32.7nMAssay Description:TR-FRET is homogeneous proximity assay where Europium-labelled anti-acetyl lysine antibody binds to the acetylated substrate labelled with biotin whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A(Human)
Aurigene Oncology

US Patent
LigandPNGBDBM722767(US20250059204, Compound 44 | US20250145637, Exampl...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent