BDBM722568 (S)-N-(4-(4-amino- 1-methyl-7-(1- (piperidin-4-yl)-1H- pyrazol-4-yl)-1H- pyrazolo[4,3- c]pyridin-3-yl)-2- (1-(4-fluorophenyl) ethoxy)phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 59

SMILES C[C@H](Oc1cc(-c2nn(C)c3c(-c4cnn(C5CCNCC5)c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1

InChI Key InChIKey=PXVYYMXFPOZTCJ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 722568   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722568((S)-N-(4-(4-amino- 1-methyl-7-(1- (piperidin-4-yl)...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722568((S)-N-(4-(4-amino- 1-methyl-7-(1- (piperidin-4-yl)...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722568((S)-N-(4-(4-amino- 1-methyl-7-(1- (piperidin-4-yl)...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent