BDBM722518 (S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyrazol-4- yl)furo[3,2-c]pyridin- 3-yl)-2-(1-(4- fluorophenyl)ethoxy) phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 9

SMILES C[C@H](Oc1cc(-c2coc3c(-c4cnn(CCO)c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1

InChI Key InChIKey=IPKCHBQTDKDWOK-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 722518   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722518((S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722518((S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyra...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722518((S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyra...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Mus musculus)
Anaxis Pharma

US Patent
LigandPNGBDBM722518((S)-N-(4-(4- amino-7-(1-(2- hydroxyethyl)-1H- pyra...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent