BDBM722401 (E)-1-(2-(2-(mesitylimino)-10-methoxy-9-(methoxy-d3)-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea ::US20250059186, Compound 1

SMILES [2H]C([2H])([2H])Oc4cc3CCn2c(cc(=Nc1c(C)cc(C)cc1C)n(CCNC(N)=O)c2=O)c3cc4OC

InChI Key InChIKey=CSOBIBXVIYAXFM-GKOSEXJESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722401   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM722401((E)-1-(2-(2-(mesitylimino)-10-methoxy-9-(methoxy-d...)
Affinity DataIC50: 50nMAssay Description:1) Prepare FAM cAMP working solution: 20 μL of FAM-Cyclic-3′, 5′-AMP stock was added to 1980 μL of PDE assay buffer. The mixture was added to all wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
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