BDBM721873 US20250059174, Example 136

SMILES Cc1ccc(-c2noc([C@H]3C[C@@H]3F)n2)cc1NC(=O)c1cnn2ccc(-c3cnn(C4COC4)c3)cc12

InChI Key InChIKey=FYONKRQUTPFGEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721873   

TargetMast/stem cell growth factor receptor Kit(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM721873(US20250059174, Example 136)
Affinity DataIC50: 100nMAssay Description:Kinase Reaction: The kinase assay was based on the recommended protocol by c-KIT Kinase Enzyme System from Promega. Recombinant human c-KIT kinase in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent