BDBM721712 US20250059172, Example 84

SMILES COC(C)(C)c4ccc(n3ncc2c(NC(=O)c1cc(CCC(=O)C(C)(C)C)ccc1Cl)cccc23)cn4

InChI Key InChIKey=SSAUJJVPHQDXIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721712   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM721712(US20250059172, Example 84)
Affinity DataIC50: 0.800nMAssay Description:mPGES-1 microsomal specimens were prepared by transiently transfecting CHO-K1 cells (DS Pharma Biomedical Co. Ltd) with a plasmid encoding human mPGE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent