BDBM721673 US20250059172, Example 45

SMILES O=C(NCc4ccc(Cl)c(C(=O)Nc1cccc2c1cnn2c3ccc(C(F)(F)F)cc3)c4)c5ccco5

InChI Key InChIKey=YGTRYEFRYODILP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721673   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM721673(US20250059172, Example 45)
Affinity DataIC50: 1.20nMAssay Description:mPGES-1 microsomal specimens were prepared by transiently transfecting CHO-K1 cells (DS Pharma Biomedical Co. Ltd) with a plasmid encoding human mPGE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent