BDBM721659 US20250059172, Example 31

SMILES O=C(Nc1cccc2c1cnn2c3ccc(C(F)(F)F)cc3)c5cc(CNC(=O)C4CCCCC4)ccc5Cl

InChI Key InChIKey=GRSLYHLZHJQMDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721659   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM721659(US20250059172, Example 31)
Affinity DataIC50: 1.60nMAssay Description:mPGES-1 microsomal specimens were prepared by transiently transfecting CHO-K1 cells (DS Pharma Biomedical Co. Ltd) with a plasmid encoding human mPGE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent