BDBM721631 US20250059172, Example 3

SMILES O=C(Nc1cccc2c1cnn2c3cccc(C(F)(F)F)c3)c5cc(CNC(=O)C4CC4)ccc5Cl

InChI Key InChIKey=OBPMKYGOURDVBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721631   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM721631(US20250059172, Example 3)
Affinity DataIC50: 1.20nMAssay Description:mPGES-1 microsomal specimens were prepared by transiently transfecting CHO-K1 cells (DS Pharma Biomedical Co. Ltd) with a plasmid encoding human mPGE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent