BDBM721589 US20250059159, Compound 115::ethyl 2-(4-(N-(1-(1-(naphthalen-1-yl)ethyl)piperidin-4-yl)-N-(2-oxo-2-((2-oxo-2-(prop-2-yn-1-ylamino)ethyl)amino)ethyl)sulfamoyl)piperazin-1-yl)acetate

SMILES CCOC(=O)CN1CCN(S(=O)(=O)N(CC(=O)NCC(=O)NCC#N)C2CCN(C(C)c3cccc4ccccc34)CC2)CC1

InChI Key InChIKey=OJIGYGNHEKWMAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721589   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Synergy Pharmaceutical Sciences

US Patent
LigandPNGBDBM721589(ethyl 2-(4-(N-(1-(1-(naphthalen-1-yl)ethyl)piperid...)
Affinity DataIC50: 100nMAssay Description:The PLpro enzyme was purified as described above and prepared in assay buffer (50 mM HEPES, pH 7.5, 0.01% Triton X-100 (v/v), 0.1 mg mL-1 BSA, and 2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent