BDBM721576 2-(N-(1-(1-(2,3-dimethylphenyl)ethyl)piperidin-4-yl)methylsulfonamido)-N-(2-oxo-2-(prop-2-yn-1-ylamino)ethyl)acetamide::US20250059159, Compound 99

SMILES C#CCNC(=O)CNC(=O)CN(C1CCN(C(C)c2cccc(C)c2C)CC1)S(C)(=O)=O

InChI Key InChIKey=RNSPWLDHNQMXIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721576   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Synergy Pharmaceutical Sciences

US Patent
LigandPNGBDBM721576(2-(N-(1-(1-(2,3-dimethylphenyl)ethyl)piperidin-4-y...)
Affinity DataIC50: 100nMAssay Description:The PLpro enzyme was purified as described above and prepared in assay buffer (50 mM HEPES, pH 7.5, 0.01% Triton X-100 (v/v), 0.1 mg mL-1 BSA, and 2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
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