BDBM721013 US12226405, Example 112

SMILES N#CC1=CN2C[C@@]3(CCSc4c3ccc(F)c4F)N=C2C(OC(F)F)=C1

InChI Key InChIKey=LLDGIISYMKLWFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721013   

TargetEndothelial PAS domain-containing protein 1(Human)
Novartis

US Patent
LigandPNGBDBM721013(US12226405, Example 112)
Affinity DataIC50: 7nMAssay Description:The scintillation proximal assay (SPA) was based on a competition binding assay with the radio-ligand N-(3-chloro-5-fluorophenyl-4-t)-4-nitrobenzo[c]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent