BDBM720969 US12226405, Example 66

SMILES N#CC1=CN2C[C@@]3(CCSc4c(F)cccc43)N=C2C(OC(F)F)=C1

InChI Key InChIKey=NRRANYADFSVEFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720969   

TargetEndothelial PAS domain-containing protein 1(Human)
Novartis

US Patent
LigandPNGBDBM720969(US12226405, Example 66)
Affinity DataIC50: 8nMAssay Description:The scintillation proximal assay (SPA) was based on a competition binding assay with the radio-ligand N-(3-chloro-5-fluorophenyl-4-t)-4-nitrobenzo[c]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent