BDBM720963 US12226405, Example 60

SMILES FC(F)OC1=CC(C(F)(F)F)=CN2C[C@@]3(N=C12)c1ccc(I)cc1OC[C@@H]3F

InChI Key InChIKey=XBLLRJDZVSWTAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720963   

TargetEndothelial PAS domain-containing protein 1(Human)
Novartis

US Patent
LigandPNGBDBM720963(US12226405, Example 60)
Affinity DataIC50: 6nMAssay Description:The scintillation proximal assay (SPA) was based on a competition binding assay with the radio-ligand N-(3-chloro-5-fluorophenyl-4-t)-4-nitrobenzo[c]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent