BDBM72094 1-(2,3-Dihydro-indol-1-yl)-2-(5,6-diphenyl-[1,2,4]triazin-3-ylsulfanyl)-ethanone::1-(2,3-dihydroindol-1-yl)-2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]ethanone::1-(2,3-dihydroindol-1-yl)-2-[(5,6-diphenyl-1,2,4-triazin-3-yl)thio]ethanone::2-[(5,6-diphenyl-1,2,4-triazin-3-yl)thio]-1-indolin-1-yl-ethanone::MLS000550742::SMR000177935::cid_3146235

SMILES O=C(CSc1nnc(-c2ccccc2)c(n1)-c1ccccc1)N1CCc2ccccc12

InChI Key InChIKey=VYWVGJDFMVEDFJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72094   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM72094(MLS000550742 | 1-(2,3-dihydroindol-1-yl)-2-[(5,6-d...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM72094(MLS000550742 | 1-(2,3-dihydroindol-1-yl)-2-[(5,6-d...)
Affinity DataIC50: 58.1nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM72094(MLS000550742 | 1-(2,3-dihydroindol-1-yl)-2-[(5,6-d...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed