BDBM720688 (R)-4-(2-(6-methoxy-1H-indol-4-yl)-7-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-methylmorpholine ::US20250051362, Compound 32

SMILES COc1cc(-c2nc(N3CCOC[C@H]3C)c3ccn(S(C)(=O)=O)c3n2)c2cc[nH]c2c1

InChI Key InChIKey=LLQPSNXUTNHFGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 720688   

TargetSerine/threonine-protein kinase ATR(Human)
Shanghai Annova Biotechnology

US Patent
LigandPNGBDBM720688((R)-4-(2-(6-methoxy-1H-indol-4-yl)-7-(methylsulfon...)
Affinity DataIC50: 5.30nMAssay Description:The inhibitory activity of the compounds on ATR kinase in vitro was determined by Mobility Shift Assay at an ATP concentration of Km using Caliper EZ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM720688((R)-4-(2-(6-methoxy-1H-indol-4-yl)-7-(methylsulfon...)
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed