BDBM720563 US20250051335, Compound 16

SMILES Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)c(Cl)c1

InChI Key InChIKey=PEJDSGDBWVOOSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 720563   

TargetTau-tubulin kinase 1(Human)
Csic

US Patent
LigandPNGBDBM720563(US20250051335, Compound 16)
Affinity DataIC50: 2.30E+3nMAssay Description:A buffer solution containing the recombinant human enzyme TTBK1 (1-1321) or TTBK2(1-450) (5-20 mU) and 50 mM Tris at pH 7.5, 0.1 mM EGTA, 0.1% p-merc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetTau-tubulin kinase 2 [1-450](Human)
Csic

US Patent
LigandPNGBDBM720563(US20250051335, Compound 16)
Affinity DataIC50: 5.72E+3nMAssay Description:A buffer solution containing the recombinant human enzyme TTBK1 (1-1321) or TTBK2(1-450) (5-20 mU) and 50 mM Tris at pH 7.5, 0.1 mM EGTA, 0.1% p-merc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent