BDBM720188 6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-triazol-5-yl]methoxy}-2-(oxolan-3-yl)-1,2,3,4-tetrahydro-2,7-naphthyridine::US20250051323, Example 29

SMILES Cc1ccc(-n2nnc(C)c2COc2cc3c(cn2)CN(C2CCOC2)CC3)cn1

InChI Key InChIKey=VABCGRSXCDHYFL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720188   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720188(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  29.7nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent