BDBM72017 US12486280, Compound A31

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@]6(CCN(S(C)(=O)=O)C6)C5)cn4)ncc3F)cc2n1C(C)C

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72017   

TargetCyclin-dependent kinase 6(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72017BDBM72017(US12486280, Compound A31)
Affinity DataKi:  1.71E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72017BDBM72017(US12486280, Compound A31)
Affinity DataKi:  1.02E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72017BDBM72017(US12486280, Compound A31)
Affinity DataIC50: 2.17E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent