BDBM719827 (S)-2-hydroxy-N-(1-(5-(2-((6- (trifluoromethyl)oxazolo[4,5- c]pyridin-2- yl)thio)acetyl)thiophen-2- yl)ethyl)acetamide::US20250051319, Compound 129

SMILES C[C@@H](NC(=O)CO)c1ccc(C(=O)CSc2nc3cnc(C(F)(F)F)cc3o2)s1

InChI Key InChIKey=LDCDRAILNRZETE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719827   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719827((S)-2-hydroxy-N-(1-(5-(2-((6- (trifluoromethyl)oxa...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent