BDBM719821 2,2,2-trifluoro-N-((5-(2-((2- (trifluoromethyl)pyrido[2,3- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)ethane-1-sulfonamide::US20250051319, Compound 123

SMILES O=C(CSc1nc(C(F)(F)F)nc2ncccc12)c1ccc(CNS(=O)(=O)CC(F)(F)F)s1

InChI Key InChIKey=KNDUFZLKBPYYJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719821   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719821(2,2,2-trifluoro-N-((5-(2-((2- (trifluoromethyl)pyr...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent