BDBM719820 N-((5-(2-((2- (trifluoromethyl)pyrido[2,3- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)cyclopropanesulfonamide::US20250051319, Compound 122

SMILES O=C(CSc1nc(C(F)(F)F)nc2ncccc12)c1ccc(CNS(=O)(=O)C2CC2)s1

InChI Key InChIKey=ULKREEAWRRZHJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719820   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719820(N-((5-(2-((2- (trifluoromethyl)pyrido[2,3- d]pyrim...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent