BDBM719781 2-hydroxy-N-((5-(2-((2-methyl-6- (1,4-oxazepan-4-yl)quinazolin-4- yl)thio)acetyl)thiophen-2- yl)methyl)acetamide::US20250051319, Compound 83

SMILES Cc1nc(SCC(=O)c2ccc(CNC(=O)CO)s2)c2cc(N3CCCOCC3)ccc2n1

InChI Key InChIKey=ICWBHNMJEZAMHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719781   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719781(2-hydroxy-N-((5-(2-((2-methyl-6- (1,4-oxazepan-4-y...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent