BDBM719746 3,3,3-trifluoro-2-hydroxy-N-((5-(2- ((2-methyl-6-(trifluoromethyl)-2H- pyrazolo[3,4-d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)propanamide::US20250051319, Compound 46

SMILES Cn1cc2c(SCC(=O)c3ccc(CNC(=O)C(O)C(F)(F)F)s3)nc(C(F)(F)F)nc2n1

InChI Key InChIKey=WCYICTOKAOSDQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719746   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719746(3,3,3-trifluoro-2-hydroxy-N-((5-(2- ((2-methyl-6-(...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent