BDBM719741 N-((5-(2-((2-methyl-6- (trifluoromethyl)-2H-pyrazolo[3,4- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)cyclopropanecarboxamide::US20250051319, Compound 41

SMILES Cn1cc2c(SCC(=O)c3ccc(CNC(=O)C4CC4)s3)nc(C(F)(F)F)nc2n1

InChI Key InChIKey=AWHNQIZKZFARRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719741   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719741(N-((5-(2-((2-methyl-6- (trifluoromethyl)-2H-pyrazo...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent