BDBM719134 6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethyl-3H-1,4-benzodiazepin-2-one (II)::US12344614, Example 2::US20250049967, Example 2

SMILES Cc1ccc2c(c1Cl)C(c1cc(O)ccc1F)=NCC(=O)N2C

InChI Key InChIKey=RHGALLXQCYCOFY-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 719134   

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  0.530nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  0.530nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  1.49nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  1.49nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  3.49nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  3.49nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  58.2nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Flumazenil at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  58.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent