BDBM719133 6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methyl-3H-1,4-benzodiazepin-2-one (I)::US12344614, Example 1::US20250049967, Example 1

SMILES CN1C(=O)CN=C(c2cc(O)ccc2F)c2c1ccc(Cl)c2Cl

InChI Key InChIKey=PAGIUELYHAPFIM-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 719133   

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  0.340nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.27nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  28.7nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Flumazenil at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  28.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  28.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent