BDBM718995 4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl]piperazin-1-yl)-N-[4-(15-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-3-nitrobenzenesulfonyl]-2-[14-oxa-2,4,10-triazatricyclo[7.5.0.0{circumflex over ( )}[3,7]]tetradeca-1(9),2,5,7-tetraen-10-yl]benzamide::US12220419, Example 51

SMILES CC1(C)CC=C(CN2CCN(c3ccc(N4CCCC(=O)c5nc6[nH]ccc6cc54)c(C(=O)NS(=O)(=O)c4ccc(NCCOCCOCCOCCOCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)c([N+](=O)[O-])c4)c3)CC2)C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=XEYZUSZBTGQIGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718995   

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM718995(4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataIC50: 0.900nMAssay Description:The fluorescence-labeled 23 amino acid peptide BH3 was purchased from CalBiochem (NLWAAQRYGRELRRMSDKFVD). An unbound Fluorescein labeled BH3 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent