BDBM718994 4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl]piperazin-1-yl)-N-(4-[[2-(4-[2-[2-(2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy)ethoxy]ethyl]piperazin-1-yl)ethyl]amino]-3-nitrobenzene sulfonyl)-2-[14-oxa-2,4,10-triazatricyclo[7.5.0.0{circumflex over ( )}[3,7]]tetradeca-1(9),2,5,7-tetraen-10-yl]benzamide::US12220419, Example 50

SMILES CC1(C)CC=C(CN2CCN(c3ccc(N4CCCC(=O)c5nc6[nH]ccc6cc54)c(C(=O)NS(=O)(=O)c4ccc(NCCN5CCN(CCOCCOCCONc6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)c([N+](=O)[O-])c4)c3)CC2)C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=FNWACTXIFFJGBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718994   

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM718994(4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataIC50: 0.600nMAssay Description:The fluorescence-labeled 23 amino acid peptide BH3 was purchased from CalBiochem (NLWAAQRYGRELRRMSDKFVD). An unbound Fluorescein labeled BH3 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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