BDBM718990 US12220419, Example 44

SMILES CC1(C)CC=C(CN2CCN(c3ccc(N4c5cc6cc[nH]c6nc5C(=O)C5CCCC54)c(C(=O)NS(=O)(=O)c4ccc(NC[C@H]5COCCO5)c([N+](=O)[O-])c4)c3)CC2)C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=RBIHVTGZHQFVMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 718990   

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM718990(US12220419, Example 44)
Affinity DataIC50: 1.30nMAssay Description:The fluorescence-labeled 23 amino acid peptide BH3 was purchased from CalBiochem (NLWAAQRYGRELRRMSDKFVD). An unbound Fluorescein labeled BH3 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM718990(US12220419, Example 44)
Affinity DataIC50: 0.800nMAssay Description:The fluorescence-labeled 23 amino acid peptide BH3 was purchased from CalBiochem (NLWAAQRYGRELRRMSDKFVD). An unbound Fluorescein labeled BH3 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent