BDBM718805 US20250042896, Compound 126

SMILES CC(NC1(C)CCC1)c1cc(C(F)(F)F)c2ncc(-c3cccc([C@]4(c5nncn5C)C[C@@H](C)C4)c3)c(=O)n2c1

InChI Key InChIKey=MMTUEJNVIFLGLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718805   

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718805(US20250042896, Compound 126)
Affinity DataIC50: 11.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent