BDBM718793 Preparation of (S)-3-(3-(3,3-difluoro-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl)phenyl)-8-methyl-6-((3-methylpiperidin-1-yl)methyl)-4H-chromen-4-one ::US20250042896, Compound 73

SMILES Cc1cc(CN2CCC[C@H](C)C2)cc2c(=O)c(-c3cccc(C4(c5nncn5C)CC(F)(F)C4)c3)coc12

InChI Key InChIKey=YTNSIQZJRWVDTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718793   

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718793(Preparation of (S)-3-(3-(3,3-difluoro-1-(4-methyl-...)
Affinity DataIC50: 64.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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