BDBM71843 2-ethyl-3-(2-furylmethyl)-8,8-dimethyl-7,10-dihydro-8H-pyrano[3'',4'':5',6']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one::MLS000096852::SMR000074563::cid_1416241

SMILES CC(C)(O)c1csc([S@](N)(=O)=NC(=O)Nc2c3c(cc4c2CCC4)CCC3)n1

InChI Key InChIKey=YKVYDTMSXDECQO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 71843   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71843BDBM71843(US11724992, Example 307 | US11724992, Compound 366...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71843BDBM71843(US11724992, Example 307 | US11724992, Compound 366...)
Affinity DataIC50: 67nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71843BDBM71843(US11724992, Example 307 | US11724992, Compound 366...)
Affinity DataIC50: 120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent