BDBM718281 US20250042889, Example 136

SMILES O=C(N[C@H]1CCCC[C@H]1Nc1c(C(=O)N2CCC(N3CCOCC3)CC2)cc(Br)cc1[N+](=O)[O-])c1cc(=O)[nH]c2ccccc12

InChI Key InChIKey=IRPYGBXBGXUGIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718281   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718281(US20250042889, Example 136)
Affinity DataIC50: 30nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent