BDBM718270 US20250042889, Example 125

SMILES C[C@@H]1CN(C(=O)c2cc(Br)cc([N+](=O)[O-])c2N[C@@H]2CCN(C(=O)c3cncc4cc(Cl)ccc34)C2)C[C@H](C)N1

InChI Key InChIKey=VYSBHBRHETWYSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718270   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718270(US20250042889, Example 125)
Affinity DataIC50: 30nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent