BDBM718179 (4R,6S)-4-((R)-3-((4-bromo-2-((S)-3-methylpiperidin-1-carbonyl)-6-nitrophenyl)amino)piperidin-1-carbonyl)-6-methylpiperidin-2-one::US20250042889, Example 33

SMILES C[C@H]1CCCN(C(=O)c2cc(Br)cc([N+](=O)[O-])c2N[C@@H]2CCCN(C(=O)[C@H]3CC(=O)N[C@@H](C)C3)C2)C1

InChI Key InChIKey=VWIBYNASEXZISP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718179   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718179((4R,6S)-4-((R)-3-((4-bromo-2-((S)-3-methylpiperidi...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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