BDBM718171 N-((1S,2R)-2-((4-bromo-2-nitro-6-(3-oxopiperazin-1-carbonyl)phenyl)amino)cyclohexyl)-7-chloroisoquinolin-4-formamide::US20250042889, Example 25

SMILES O=C1CN(C(=O)c2cc(Br)cc([N+](=O)[O-])c2N[C@@H]2CCCC[C@@H]2NC(=O)c2cncc3cc(Cl)ccc23)CCN1

InChI Key InChIKey=PSCYJSFMWIFTBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718171   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718171(N-((1S,2R)-2-((4-bromo-2-nitro-6-(3-oxopiperazin-1...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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