BDBM718167 (5-Bromo-2-((R)-5-(5-(methylamino) nicotinoyl)-5-azaspiro[2.4]heptan-7-yl)amino)-3-nitrophenyl)((3R,5S)-3,5-dimethylpiperazin-1-yl)methanone::US20250042889, Example 21

SMILES CNc1cncc(C(=O)N2C[C@H](Nc3c(C(=O)N4C[C@@H](C)N[C@@H](C)C4)cc(Br)cc3[N+](=O)[O-])C3(CC3)C2)c1

InChI Key InChIKey=UGWXUYBXJIKRCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718167   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718167((5-Bromo-2-((R)-5-(5-(methylamino) nicotinoyl)-5-a...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent