BDBM718162 N-((1S,2R)-2-((4-bromo-2-(4,4-difluoropiperidin-1-carbonyl)-6-nitrophenyl)amino)cyclohexyl)-2-oxo-1,2-dihydroquinolin-4-formamide::US20250042889, Example 16

SMILES O=C(N[C@H]1CCCC[C@H]1Nc1c(C(=O)N2CCC(F)(F)CC2)cc(Br)cc1[N+](=O)[O-])c1cc(=O)[nH]c2ccccc12

InChI Key InChIKey=ZLQYHZYNIJZRMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718162   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718162(N-((1S,2R)-2-((4-bromo-2-(4,4-difluoropiperidin-1-...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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