BDBM718161 ((3R)-3-((2-(3-azabicyclo[3.1.0]hexan-3-carbonyl)-4-bromo-6-nitrophenyl)amino)piperidin-1-yl)(isoquinolin-4-yl)methanone::US20250042889, Example 15

SMILES O=C(c1cc(Br)cc([N+](=O)[O-])c1N[C@@H]1CCCN(C(=O)c2cncc3ccccc23)C1)N1CC2CC2C1

InChI Key InChIKey=QRLADDUTSYQUQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718161   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718161(((3R)-3-((2-(3-azabicyclo[3.1.0]hexan-3-carbonyl)-...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent