BDBM718155 N-((1S,2R)-2-((4-Bromo-2-(piperidin-1-carbonyl)-6-(trifluoromethyl)phenyl)amino)cyclohexyl) isoquinolin-4-formamide::US20250042889, Example 9

SMILES O=C(N[C@H]1CCCC[C@H]1Nc3c(C(=O)N2CCCCC2)cc(Br)cc3C(F)(F)F)c4cncc5ccccc45

InChI Key InChIKey=CCLLTTOUYJGASC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718155   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718155(N-((1S,2R)-2-((4-Bromo-2-(piperidin-1-carbonyl)-6-...)
Affinity DataIC50: 30nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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